For a dose of new San Antonio, head to The Historic Pearl Brewery, a complex of restaurants, shops and park space at the renovated Pearl Brewery, once the state’s largest brewery founded in 1881. The team behind the multi-use complex has gathered the city’s top tastemakers into one, 22-acre spot close to downtown and perched on the northern bank of the River Walk. The stunning space has soaring ceilings and is stocked with native entrepreneurs, including Il Sogno Osteria, chef Andrew Weissman’s paean to Roman and Florentine cooking. Commanding serious marquee value is the new Culinary Institute of America’s campus at the Pearl, adjacent to the stables where the old brewery housed its draft horses. It’s easy to while away an afternoon—grab a table and margaritas outside at La Gloria Ice House, which serves Mexican street foods and peruse your purchase from The Twig, a popular indie bookstore.